Cleavage of 4-(2, 4-Dinitrophenoxy)-3-Methoxybenzaldehyde with Amines

Abstract

Diphenyl ethers are well known and important motifs in organic chemistry that were synthesized more than a century ago. Their use as flame retarding agents, antimalarial and antifungal agent is well known. Diphenyl ethers represent one of very stable motifs due to their aromatic nature. The work presented in the thesis explores cleavage of diphenyl ether in the presence of amines under very mild conditions. The diphenyl ethers, 4-(2,4-dinitrophenoxy)-3- methoxybenzaldehyde was synthesized by known procedure and its cleavage was done with different amines in the presence of methanol. Interestingly, cleavage was preferred reaction over Schiff base formation. All the synthesized compounds were characterized by TLC and 1H and 13C NMR.