Comparison of DNA Sequences Base Composition In Coding And Non-Coding Seqeunces

Abstract

DNA stores genetic information within the variety of sequence of 4 bases A, T, G and C. Just in case of RNA viruses, it's hold on within the variety of RNA base sequence comprising of G, A, U and C. The organization of genomes of prokaryotes and eukaryotes are simple and complex respectively. GC content typically calculated as a percentage value and sometimes known as G+C quantitative relation or rate-ratio. GC-content proportion is calculated as Count (G + C)/Count (A + T + G + C) * 100 percent. Here we calculated the GC% for both coding and non-coding sequences of prokaryotes and exons and introns of eukaryotes and observed that in both the cases the GC% of coding region and exons regions are always higher than non-coding or introns region. We analysed the coefficient of variation and displacement in 2D-random walk of DNA sequence for the data and analysed that in prokaryotes the coding is higher while in the case on eukaryotes introns have higher coefficient of variation and 2D-random walk displacement so no inference can be drawn because the coefficient of variation and random walk seems to be getting affected by the length of the sequence.