Detection of Reproductive tract infections in symptomatic and Asymptomatic women

Abstract

Reproductive tract infections (RTIs) are the infection of the reproductive genital tract. RTIs are responsible for the loss of healthy life in sexually active and reproductive-age women in developing countries. The most commonly predominant RTIs causing agents are C. trachomatis, N. gonorrhoea, T. vaginalis, and Human Papillomavirus. Therefore, an accurate diagnosis of these infections is required in asymptomatic and symptomatic women. The aim of this study is to know the prevalence of various RTIs, its correlation with clinical features. Among the recruited individuals, 40% were infected with RTIs out of which two-thirds of the participants were symptomatic. Afterward, the co-infection 13 (3.85%) was highly noted for T. vaginalis and Human Papillomavirus. Our data indicated a total prevalence of 3%, 6%, and 31% for C. trachomatis, T. vaginalis, and Human Papillomavirus, respectively. Subsequently, Human Papillomavirus showed a high significance in the correlation between symptomatic and asymptomatic women. On further analysis, human TNF-α was studied and a high level of TNF-α was monitored in individuals infected with RTIs compared to the controls. Hence, symptomatic women are at high risk of RTIs and successful intervention requires accurate and confirmatory diagnostic approach