Efficient approach for the synthesis of threo-α-amino epoxides
| dc.contributor.author | Sharma, Bandhana | |
| dc.contributor.supervisor | Pandey, Satyendra Kumar | |
| dc.date.accessioned | 2013-09-03T07:28:58Z | |
| dc.date.available | 2013-09-03T07:28:58Z | |
| dc.date.issued | 2013-09-03T07:28:58Z | |
| dc.description | Master of Science, Dissertation | en |
| dc.description.abstract | A practical and distereoselective synthesis of threo-α-amino epoxides 1a has been achieved employing (S,S)-DACH-Phenyl Trost Ligand and m-CPBA epoxidation. The synthesis strategy describe as significant potential for further extension to other isomers and related analogues including natural products, non-peptidic protease inhibitors, synthesis of hydroxyethylamine, hydroxyethylene dipeptide isosters, anti cancer and antibiotic products, novel amino acids, NMDA antagonists, potent inhibitors of aspartic acid proteases such as rennin or HIV-protease | en |
| dc.description.sponsorship | School of Chemistry and Biochemistry, Thapar University, Patiala | en |
| dc.format.extent | 1605037 bytes | |
| dc.format.mimetype | application/pdf | |
| dc.identifier.uri | http://hdl.handle.net/10266/2390 | |
| dc.language.iso | en | en |
| dc.subject | S,S)-DACH-Phenyl | en |
| dc.subject | Trost Ligand | en |
| dc.subject | epoxidation | en |
| dc.subject | threo-α-aminoepoxides | en |
| dc.title | Efficient approach for the synthesis of threo-α-amino epoxides | en |
| dc.type | Thesis | en |