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Title: Synthesis and Characterization of Pyrazole and Perimidine Conjugates as Anticancer Agents
Authors: Kaur, Jasleen
Supervisor: Paul, Kamaldeep
Keywords: Perimidine;Pyrazole;Molecular hybridization;alkylation
Issue Date: 25-Jul-2018
Abstract: ABSTRACT Despite the development of many anticancer drugs, cancer is still most evident cause of death. So, now instead of using single-target therapy for the treatment of cancer, molecular hybridization methodology is useful which involves grouping of different pharmacophoric moieties to generate a new and effective anticancer hybrid drug. Heterocyclic moieties show significant role in treatment of cancer. We have synthesized a series of pyrazole-perimidine hybrids as potential anticancer agents. These compounds were further characterized by 1H and 13C NMR spectrometry. Evaluation of these hybrids for the anticancer activity is in progress.
Appears in Collections:Masters Theses@SCBC

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